Routes of Transmission
A. General Concepts
1. Cycle of infection = All factors involved in the spread
of disease
a. Infectious organism: Pathogen
b. Reservoir of infection: Place where organisms can
thrive
c. Portal of exit: Any avenue available to exit the
body
d. Susceptible host: Person at risk for infection
e. Portal of entry: Any avenue available to enter the
body
f. Mode of transportation: Route taken by pathogens
from reservoir to susceptible host
2. Healthcare Acquired Infections (HAIs)
a. Also called nosocomial infections
b. Approximately 2 million persons acquire HAI per
year
c. CDC estimates 90,000 annual deaths because of
HAIs
d. Most common route of infection involves urinary
catheter
B. Direct Contact Transmission:
1. infected person touches susceptible host, allowing the
infectious organisms to come in contact with susceptible
tissues
2. Fomite: An object that has been in contact with
pathogens comes in contact with susceptible
tissues
C. Airborne transmission: Droplets and dust that are
able to remain suspended in air for extended periods
of time
D. Droplet transmission: Transmitted primarily by coughs,
sneezes, or other methods of spraying onto a nearby
host
E. Common vehicle transmission: Transmitted primarily by
contaminated items such as food, water, medications,
devices, and equipment
F. Vector-borne transmission: Animal or insect contains and
transmits infectious organism to humans
Standard Precautions
A. First tier of transmission-based isolation precautions
B. System that uses barriers to prevent contact with blood,
all body fluids, nonintact skin, and mucous membranes,
if there is a chance of transmission of infection
C. Assumes all body fluids are sources of infection
D. Assumes all patients are infected
E. Guidelines
1. Always wear gloves when any chance of being in contact
with body substances exists
2. Protect clothing by wearing a protective gown or
plastic apron, if a chance of coming in contact with
body substances exists
3. Masks or eye protection must be worn if a chance of
body-substances splashing exists
4. Handwashing is the most effective method to prevent
the spread of infection
5. Uncapped needle syringe units and all sharps must be
discarded in biohazard containers
6. If any contact is made with body substances, the
entire area contacted must be washed completely
with bleach
7. Contaminated articles must be disposed of properly
8. Needles should never be recapped but should be
placed with the syringe in a sharps container
9. Protective masks or mouthpieces should be used when
performing cardiopulmonary resuscitation (CPR), if
providing breaths in addition to chest compression.
Medical Asepsis
A. Includes proper hand hygiene
1. Use alcohol-based hand sanitizer for 15 seconds
2. Conventional handwashing (duration): 30 to 60
seconds
a. Adjust water temperature
b. Wet hands
c. Lather antimicrobial soap into hands and fingers
for at least 20 seconds
d. Rinse clear
e. Dry thoroughly
f. Turn off faucet with paper towel when handles are
present
3. No wearing of artificial nails
B. Microorganisms have been eliminated as much as possible
C. Water and chemicals are used for the disinfection
Surgical Asepsis
A. Complete removal of all organisms from equipment and
the environment in which patient care is conducted
B. Includes complete sterilization of equipment and appropriate
skin preparation
1. Chemical sterilization: Soaking objects in germicidal
solution
2. Boiling: Sterilization with moist heat
• Check identification bracelet to ensure that correct
patient is being transferred
• Explain transfer procedure to patient to gain
cooperation and alleviate fear
• Always use proper body mechanics
• Ensure all appropriate brakes are applied
• Make creative use of sheets and helpers when moving
Patient
3. Dry heat: Placing objects in an oven at temperatures
greater than 329° F
4. Gas sterilization: Items are exposed to a mixture of
gases, which do not harm the materials
5. Autoclaving: Steam sterilization under pressure; most
convenient way to sterilize materials
Sterile Technique
A. Steps to follow in the opening of sterile packs
1. Check expiration date
2. Place pack on a clean surface
3. Break seal and open pack
4. Unfold the first corner of the pack away from you
5. Unfold both sides
6. Pull front portion of the wrap toward you and drop
it
7. Never touch the inner surface
8. If there is an inner wrap, open it using the same
method
9. Separately wrapped sterile items may be added to
the sterile field by opening the pack and allowing
the items to drop onto the sterile field
10. Never allow the container to touch the sterile field
B. Pouring liquids into containers in a sterile field
1. Carefully determine the contents of the container
2. Pour a small amount into a waste receptacle to cleanse
the lip of the bottle
3. Pour the medium into the receptacle, being careful
not to touch the sterile field in the process
C. Sterile objects or fields touched by unsterile objects or
persons are immediately contaminated
D. Avoid reaching across sterile fields
E. If you suspect that an object is contaminated, assume
that it is contaminated
F. Always assume that damp items are contaminated
G. Do not invade the space between a physician and the
sterile field
H. Never abandon a sterile field; it must be under direct
observation at all times
I. Never turn your back on a sterile field
J. Remember: Only from your waist up and in front is
sterile
Gloving
A. Wash hands thoroughly
B. Open outer package containing gloves
C. Open inner package, exposing gloves
D. Approach glove from open end, and touch only inner
surface with opposite hand
E. Put on glove, touching only the folded cuff
F. Pick up other glove with gloved hand under the cuff
G. Place second glove on other hand, and unfold cuff
H. Carefully unfold cuff on both gloves
I. Always keep hands in front of the body without touching
body covering or placing hands under arms
Types of Transmission-Based Precautions
A. Airborne precautions—in addition to standard
precautions
1. Wash hands before patient care
2. Workers and visitors entering patient’s room must
wear particulate respirators
3. Wash hands after patient care
B. Droplet precautions—in addition to standard precautions
1. Wash hands before patient care
2. Surgical masks required for persons coming in close
contact with patient
3. Wash hands after patient care
C. Contact precautions—in addition to standard precautions
1. Wash hands before patient care
2. gloves, and gowns are indicated for individuals coming
in contact with patient
3. Wash hands after patient care